I am remediating the Nessus findings relating to weak protocols and cipher suites. Basically disabling TLS 1.0 protocols and 3DES-CBC3 cipher suite. This will serve as a note for me for future reference.

PowerShell To disable TLS 1.0
https://dirteam.com/sander/2019/07/30/howto-disable-weak-protocols-cipher-suites-and-hashing-algorithms-on-web-application-proxies-ad-fs-servers-and-windows-servers-running-azure-ad-connect/

$SChannelRegPath = “HKLM:\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols”New-Item $SChannelRegPath -Name “TLS 1.0”
New-Item $SChannelRegPath”\TLS 1.0″ -Name SERVER
New-ItemProperty -Path $SChannelRegPath”\TLS 1.0\SERVER” –Name Enabled -Value 0 -PropertyType DWORD

Registry key to disable weak cipher suites. Save the following as registry keys and merge it. Note: before making any changes to the registry keys, make sure you take a backup by exporting the keys.
Windows Registry Editor Version 5.00
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Client]
“Enabled”=dword:00000001
“DisabledByDefault”=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Server]
“Enabled”=dword:00000001
“DisabledByDefault”=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.1\Client]
“Enabled”=dword:00000001
“DisabledByDefault”=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.1\Server]
“Enabled”=dword:00000001
“DisabledByDefault”=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\SSL 2.0\Server]
“DisabledByDefault”=dword:00000001
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\SSL 3.0\Server]
“DisabledByDefault”=dword:00000001
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\KeyExchangeAlgorithms\Diffie-Hellman]
“ServerMinKeyBitLength”=dword:00000800

[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Ciphers\RC4 128/128]
“Enabled”=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Ciphers\RC4 40/128]
“Enabled”=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Ciphers\RC4 56/128]
“Enabled”=dword:00000000

You can also disable weak ciphers and algorithms using PowerShell:
Get-TlsCipherSuite | Format-Table Name,

Find out the cipher flagged by Nessus and disable using the following PowerShell command:
Disable-TlsCipherSuite -Name “TLS_RSA_WITH_3DES_EDE_CBC_SHA”